SIVEXTRO vs TRIMETHOPRIM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. SIVEXTRO and TRIMETHOPRIM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SIVEXTRO	TRIMETHOPRIM
Rating	72/100	56/100
Pharmacy pays	—	~$35.33 /30
Type	RX	RX
Active ingredient	TEDIZOLID PHOSPHATE	TRIMETHOPRIM
Manufacturer	Cubist Pharms LLC	Teva
Dosage forms	Injectable, Tablet	Tablet
Drug class	—	Dihydrofolate Reductase Inhibitor Antibacterial
Boxed warning	None	None
Half-life	—	about 8 to 10 hours
Treats	Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases	Bronchitis, Escherichia Coli Infections, Klebsiella Infections

sivextro trimethoprim

Rating

72/100

56/100

Pharmacy pays

—

~$35.33 /30

Type

Active ingredient

TEDIZOLID PHOSPHATE

TRIMETHOPRIM

Manufacturer

Cubist Pharms LLC

Teva

Dosage forms

Injectable, Tablet

Tablet

Drug class

—

Dihydrofolate Reductase Inhibitor Antibacterial

Boxed warning

None

Half-life

—

about 8 to 10 hours

Treats

Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

Bronchitis, Escherichia Coli Infections, Klebsiella Infections

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Frequently asked questions

Which is better-rated, Sivextro or Trimethoprim?

By our independent rating, Sivextro scores higher — 3.6 vs 2.8 out of 5 for Trimethoprim. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Sivextro and Trimethoprim?

Sivextro contains Tedizolid Phosphate, while Trimethoprim contains Trimethoprim — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.