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SILDENAFIL CITRATE vs TADALAFIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. SILDENAFIL CITRATE and TADALAFIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

$0.11 /mL
~$4.43 /30

Type

RX
RX

Active ingredient

SILDENAFIL CITRATE
TADALAFIL

Dosage forms

Tablet
Tablet

Drug class

Phosphodiesterase 5 Inhibitor
Phosphodiesterase 5 Inhibitor

Boxed warning

None
None

Half-life

about 4 hours
about 17.5 hours

Treats

Pulmonary Hypertension, Vasculogenic Impotence
Pulmonary Hypertension, Vasculogenic Impotence

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Frequently asked questions

What is the difference between Sildenafil Citrate and Tadalafil?

Sildenafil Citrate contains Sildenafil Citrate, while Tadalafil contains Tadalafil — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.