SAPHRIS vs SECUADO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. SAPHRIS and SECUADO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SAPHRIS	SECUADO
Rating	70/100	New
Pharmacy pays	~$73.98 /30	~$73.98 /30
Type	RX	RX
Active ingredient	ASENAPINE MALEATE	ASENAPINE
Manufacturer	Abbvie	Hisamitsu
Dosage forms	Tablet	Film, extended release
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	about 24 hours (terminal/elimination half-life)	about 24 hours (terminal/elimination half-life)
Treats	Bipolar Disorder, Schizophrenia	Bipolar Disorder, Schizophrenia

saphris secuado

Rating

70/100

New

Pharmacy pays

~$73.98 /30

Type

Active ingredient

ASENAPINE MALEATE

ASENAPINE

Manufacturer

Abbvie

Hisamitsu

Dosage forms

Tablet

Film, extended release

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

about 24 hours (terminal/elimination half-life)

Treats

Bipolar Disorder, Schizophrenia

Frequently asked questions

Which is cheaper, Saphris or Secuado?

Pharmacies pay about the same to acquire either one — roughly $73.98 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Saphris and Secuado?

Saphris contains Asenapine Maleate, while Secuado contains Asenapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.