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RYTHMOL vs RYTHMOL SR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

~$10.51 /30
~$10.51 /30

Type

RX
RX

Active ingredient

PROPAFENONE HYDROCHLORIDE
PROPAFENONE HYDROCHLORIDE

Dosage forms

Tablet
Capsule, extended release

Drug class

Antiarrhythmic
Antiarrhythmic

Boxed warning

None
None

Half-life

about 2 to 10 hours (immediate-release) in the ~90% of adults who are extensive CYP2D6 metabolizers
about 2 to 10 hours (immediate-release) in the ~90% of adults who are extensive CYP2D6 metabolizers

Treats

Atrial Fibrillation, Supraventricular Tachycardia
Atrial Fibrillation, Supraventricular Tachycardia

Frequently asked questions

Which is better-rated, Rythmol or Rythmol SR?

Rythmol and Rythmol SR are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Rythmol or Rythmol SR?

Pharmacies pay about the same to acquire either one — roughly $10.51 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Rythmol and Rythmol SR?

Both Rythmol and Rythmol SR share the active ingredient Propafenone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.