PROPRANOLOL HYDROCHLORIDE vs TRANDATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PROPRANOLOL HYDROCHLORIDE and TRANDATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PROPRANOLOL HYDROCHLORIDE	TRANDATE
Rating	New	New
Pharmacy pays	~$2.49 /30	~$4.36 /30
Type	RX	RX
Active ingredient	PROPRANOLOL HYDROCHLORIDE	LABETALOL HYDROCHLORIDE
Manufacturer	Chartwell Rx	Sebela Ireland Ltd
Dosage forms	Injectable, Tablet	Tablet
Drug class	Beta-Adrenergic Blocker	Beta-Adrenergic Blocker
Boxed warning	None	None
Half-life	about 3 to 6 hours (plasma half-life, immediate-release, in healthy adults)	about 6 to 8 hours after an oral dose (about 5.5 hours after an intravenous dose)
Treats	Angina Pectoris, Esophageal and Gastric Varices, Heart Failure	Angina Pectoris, Heart Failure, Malignant Hypertension

propranolol hydrochloride trandate

Rating

New

Pharmacy pays

~$2.49 /30

~$4.36 /30

Type

Active ingredient

PROPRANOLOL HYDROCHLORIDE

LABETALOL HYDROCHLORIDE

Manufacturer

Chartwell Rx

Sebela Ireland Ltd

Dosage forms

Injectable, Tablet

Tablet

Drug class

Beta-Adrenergic Blocker

Boxed warning

None

Half-life

about 3 to 6 hours (plasma half-life, immediate-release, in healthy adults)

about 6 to 8 hours after an oral dose (about 5.5 hours after an intravenous dose)

Treats

Angina Pectoris, Esophageal and Gastric Varices, Heart Failure

Angina Pectoris, Heart Failure, Malignant Hypertension

Frequently asked questions

Which is cheaper, Propranolol Hydrochloride or Trandate?

Propranolol Hydrochloride costs pharmacies less to acquire — about $2.49 vs $4.36 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Propranolol Hydrochloride and Trandate?

Propranolol Hydrochloride contains Propranolol Hydrochloride, while Trandate contains Labetalol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.