PROMETHAZINE HYDROCHLORIDE vs THORAZINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. PROMETHAZINE HYDROCHLORIDE and THORAZINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PROMETHAZINE HYDROCHLORIDE	THORAZINE
Rating	New	70/100
Pharmacy pays	~$1.53 /30	~$12.04 /30
Type	RX	RX
Active ingredient	PROMETHAZINE HYDROCHLORIDE	CHLORPROMAZINE HYDROCHLORIDE
Manufacturer	Sun Pharm Inds Inc	Glaxosmithkline
Dosage forms	Injectable, Solution, Syrup, Tablet	Tablet, Capsule, extended release
Drug class	Phenothiazine	Phenothiazine
Boxed warning	None	None
Half-life	about 9 to 16 hours	—
Treats	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness	Anxiety Disorders, Child Behavior Disorders, Hiccup

promethazine hydrochloride thorazine

Rating

New

70/100

Pharmacy pays

~$1.53 /30

~$12.04 /30

Type

Active ingredient

PROMETHAZINE HYDROCHLORIDE

CHLORPROMAZINE HYDROCHLORIDE

Manufacturer

Sun Pharm Inds Inc

Glaxosmithkline

Dosage forms

Injectable, Solution, Syrup, Tablet

Tablet, Capsule, extended release

Drug class

Phenothiazine

Boxed warning

None

Half-life

about 9 to 16 hours

—

Treats

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Anxiety Disorders, Child Behavior Disorders, Hiccup

Frequently asked questions

Which is cheaper, Promethazine Hydrochloride or Thorazine?

Promethazine Hydrochloride costs pharmacies less to acquire — about $1.53 vs $12.04 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Promethazine Hydrochloride and Thorazine?

Promethazine Hydrochloride contains Promethazine Hydrochloride, while Thorazine contains Chlorpromazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.