PROMETHAZINE HYDROCHLORIDE vs PROMETHAZINE PLAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	PROMETHAZINE HYDROCHLORIDE	PROMETHAZINE PLAIN
Rating	New	New
Pharmacy pays	~$1.53 /30	~$1.53 /30
Type	RX	RX
Active ingredient	PROMETHAZINE HYDROCHLORIDE	PROMETHAZINE HYDROCHLORIDE
Manufacturer	Sun Pharm Inds Inc	Pharmobedient
Dosage forms	Injectable, Solution, Syrup, Tablet	Syrup
Drug class	Phenothiazine	Phenothiazine
Boxed warning	None	Boxed warning
Half-life	about 9 to 16 hours	about 9 to 16 hours
Treats	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

promethazine hydrochloride promethazine plain

Rating

New

Pharmacy pays

~$1.53 /30

Type

Active ingredient

PROMETHAZINE HYDROCHLORIDE

Manufacturer

Sun Pharm Inds Inc

Pharmobedient

Dosage forms

Injectable, Solution, Syrup, Tablet

Syrup

Drug class

Phenothiazine

Boxed warning

None

Boxed warning

Half-life

about 9 to 16 hours

Treats

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

Which is cheaper, Promethazine Hydrochloride or Promethazine Plain?

Pharmacies pay about the same to acquire either one — roughly $1.53 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Promethazine Hydrochloride and Promethazine Plain?

Both Promethazine Hydrochloride and Promethazine Plain share the active ingredient Promethazine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.