PROBUPHINE vs SUBUTEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	PROBUPHINE	SUBUTEX
Rating	New	New
Pharmacy pays	~$683.94 /30	~$683.94 /30
Type	RX	RX
Active ingredient	BUPRENORPHINE HYDROCHLORIDE	BUPRENORPHINE HYDROCHLORIDE
Manufacturer	Reacx Pharms	Indivior
Dosage forms	Implant	Tablet
Drug class	Partial Opioid Agonist	Partial Opioid Agonist
Boxed warning	None	None
Treats	Heroin Dependence, Pain	Heroin Dependence, Pain

probuphine subutex

Rating

New

Pharmacy pays

~$683.94 /30

Type

Active ingredient

BUPRENORPHINE HYDROCHLORIDE

Manufacturer

Reacx Pharms

Indivior

Dosage forms

Implant

Tablet

Drug class

Partial Opioid Agonist

Boxed warning

None

Treats

Heroin Dependence, Pain

Frequently asked questions

Which is cheaper, Probuphine or Subutex?

Pharmacies pay about the same to acquire either one — roughly $683.94 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Probuphine and Subutex?

Both Probuphine and Subutex share the active ingredient Buprenorphine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.