Skip to content
ppharmaranks
Menu

BUPRENORPHINE HYDROCHLORIDE vs PROBUPHINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

72/100
New

Pharmacy pays

~$683.94 /30
~$683.94 /30

Type

RX
RX

Active ingredient

BUPRENORPHINE HYDROCHLORIDE
BUPRENORPHINE HYDROCHLORIDE

Manufacturer

Dosage forms

Injectable, Solution, Tablet
Implant

Drug class

Partial Opioid Agonist
Partial Opioid Agonist

Boxed warning

None
None

Treats

Heroin Dependence, Pain
Heroin Dependence, Pain

Frequently asked questions

Which is cheaper, Buprenorphine Hydrochloride or Probuphine?

Pharmacies pay about the same to acquire either one — roughly $683.94 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Buprenorphine Hydrochloride and Probuphine?

Both Buprenorphine Hydrochloride and Probuphine share the active ingredient Buprenorphine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.