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PRIMSOL vs TRIMETHOPRIM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PRIMSOL and TRIMETHOPRIM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
56/100

Pharmacy pays

~$35.33 /30
~$35.33 /30

Type

RX
RX

Active ingredient

TRIMETHOPRIM HYDROCHLORIDE
TRIMETHOPRIM

Manufacturer

Dosage forms

Solution
Tablet

Drug class

Dihydrofolate Reductase Inhibitor Antibacterial
Dihydrofolate Reductase Inhibitor Antibacterial

Boxed warning

None
None

Half-life

about 8 to 10 hours
about 8 to 10 hours

Treats

Bronchitis, Escherichia Coli Infections, Klebsiella Infections
Bronchitis, Escherichia Coli Infections, Klebsiella Infections

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Frequently asked questions

Which is cheaper, Primsol or Trimethoprim?

Pharmacies pay about the same to acquire either one — roughly $35.33 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Primsol and Trimethoprim?

Primsol contains Trimethoprim Hydrochloride, while Trimethoprim contains Trimethoprim — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.