PIOGLITAZONE vs TRIGLIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PIOGLITAZONE and TRIGLIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PIOGLITAZONE	TRIGLIDE
Rating	New	New
Pharmacy pays	~$2.77 /30	~$3.45 /30
Type	RX	RX
Active ingredient	PIOGLITAZONE HYDROCHLORIDE	FENOFIBRATE
Manufacturer	Alphapharm	Jagotec
Dosage forms	Tablet	Tablet
Drug class	Peroxisome Proliferator Receptor Alpha Agonist	Peroxisome Proliferator Receptor Alpha Agonist
Boxed warning	Boxed warning	None
Half-life	about 3 to 7 hours (parent drug)	about 20 hours — but that is the half-life of fenofibric acid, the active form, not of fenofibrate itself
Treats	Type 2 Diabetes Mellitus	Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

pioglitazone triglide

Rating

New

Pharmacy pays

~$2.77 /30

~$3.45 /30

Type

Active ingredient

PIOGLITAZONE HYDROCHLORIDE

FENOFIBRATE

Manufacturer

Alphapharm

Jagotec

Dosage forms

Tablet

Drug class

Peroxisome Proliferator Receptor Alpha Agonist

Boxed warning

None

Half-life

about 3 to 7 hours (parent drug)

about 20 hours — but that is the half-life of fenofibric acid, the active form, not of fenofibrate itself

Treats

Type 2 Diabetes Mellitus

Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

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Frequently asked questions

Which is cheaper, Pioglitazone or Triglide?

Pioglitazone costs pharmacies less to acquire — about $2.77 vs $3.45 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Pioglitazone and Triglide?

Pioglitazone contains Pioglitazone Hydrochloride, while Triglide contains Fenofibrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.