triglide

How long does Fenofibrate stay in your body?

The elimination half-life of fenofibrate is about 20 hours — but that is the half-life of fenofibric acid, the active form, not of fenofibrate itself — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Fenofibrate is a prodrug. The label states it "is a pro-drug of the active chemical moiety fenofibric acid" and that after an oral dose it is "rapidly hydrolyzed by esterases to the active metabolite, fenofibric acid; no unchanged fenofibrate is detected in plasma." So there is no parent half-life to report — the label gives only one figure: "Fenofibric acid is eliminated with a half-life of 20 hours, allowing once daily dosing." That 20 hours is the elimination (terminal) half-life of the active moiety; the label reports no separate distribution phase. Kidney function matters: the label says patients with mild to moderate renal impairment (eGFR 30–59 mL/min/1.73m2) had similar exposure but "an increase in the half-life for fenofibric acid" compared with healthy subjects (it does not say by how much), and severe impairment (eGFR under 30) showed a 2.7-fold increase in exposure with accumulation on chronic dosing — the label says to avoid fenofibrate in severe renal impairment and to reduce the dose in mild-to-moderate. Older adults: in volunteers aged 77–87 the oral clearance of fenofibric acid was 1.2 L/h versus 1.1 L/h in young adults, i.e. essentially unchanged, so no age-related prolongation is described in those with normal renal function. Liver impairment: the label states no pharmacokinetic studies have been conducted in hepatic impairment, so the half-life there is unknown.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: FENOFIBRATE tablet — DailyMed label, §12.3 Pharmacokinetics.

Frequently asked questions

What does Triglide treat?

Triglide (Fenofibrate) may be used to treat coronary artery disease, hypercholesterolemia, hyperlipoproteinemias, hypertriglyceridemia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How much does Triglide cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $3.45 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Actos — about $2.77 on the same basis.

Is there a coupon or discount for Triglide?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Triglide. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Triglide?

Triglide is marketed by Jagotec. You can see Jagotec's full profile, rating, and other products on pharmaranks.

Is Triglide a brand-name or generic drug?

Triglide is a brand-name product with the active ingredient Fenofibrate. Lower-cost generic equivalents containing Fenofibrate are available — ask your pharmacist.

Is Triglide available over the counter?

No. Triglide is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Triglide come in?

Triglide is currently marketed as tablet, per the FDA's National Drug Code Directory.

What class of drug is Triglide?

Triglide is classified as peroxisome proliferator receptor alpha agonist, per the FDA's Established Pharmacologic Class.

Is Triglide FDA-registered?

Triglide is on record with the U.S. FDA under application number NDA021350. You can verify this on its official FDA label.