PENICILLIN G SODIUM vs UNIPEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. PENICILLIN G SODIUM and UNIPEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PENICILLIN G SODIUM	UNIPEN
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLIN G SODIUM	NAFCILLIN SODIUM
Manufacturer	Bristol Myers Squibb	Wyeth Ayerst
Dosage forms	Injectable	Injectable
Drug class	Penicillin-Class Antibacterial	Penicillin-Class Antibacterial
Boxed warning	None	None
Treats	Actinomycosis, Anthrax, Botulism	Cellulitis, Bacterial Endocarditis, Osteomyelitis

penicillin g sodium unipen

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

PENICILLIN G SODIUM

NAFCILLIN SODIUM

Manufacturer

Bristol Myers Squibb

Wyeth Ayerst

Dosage forms

Injectable

Drug class

Penicillin-Class Antibacterial

Boxed warning

None

Treats

Actinomycosis, Anthrax, Botulism

Cellulitis, Bacterial Endocarditis, Osteomyelitis

Frequently asked questions

What is the difference between Penicillin G Sodium and Unipen?

Penicillin G Sodium contains Penicillin G Sodium, while Unipen contains Nafcillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.