PENICILLIN G POTASSIUM vs UNIPEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PENICILLIN G POTASSIUM and UNIPEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PENICILLIN G POTASSIUM	UNIPEN
Rating	56/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PENICILLIN G POTASSIUM	NAFCILLIN SODIUM
Manufacturer	Teva	Wyeth Ayerst
Dosage forms	Injectable, Solution	Injectable
Drug class	Penicillin-Class Antibacterial	Penicillin-Class Antibacterial
Boxed warning	None	None
Treats	Actinomycosis, Anthrax, Botulism	Cellulitis, Bacterial Endocarditis, Osteomyelitis

penicillin g potassium unipen

Rating

56/100

New

Pharmacy pays

—

Type

Active ingredient

PENICILLIN G POTASSIUM

NAFCILLIN SODIUM

Manufacturer

Teva

Wyeth Ayerst

Dosage forms

Injectable, Solution

Injectable

Drug class

Penicillin-Class Antibacterial

Boxed warning

None

Treats

Actinomycosis, Anthrax, Botulism

Cellulitis, Bacterial Endocarditis, Osteomyelitis

Frequently asked questions

What is the difference between Penicillin G Potassium and Unipen?

Penicillin G Potassium contains Penicillin G Potassium, while Unipen contains Nafcillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.