OPANA ER vs ULTIVA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. OPANA ER and ULTIVA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OPANA ER	ULTIVA
Rating	New	70/100
Pharmacy pays	~$36.74 /30	—
Type	RX	RX
Active ingredient	OXYMORPHONE HYDROCHLORIDE	REMIFENTANIL HYDROCHLORIDE
Manufacturer	Endo Operations	Mylan Institutional
Dosage forms	Tablet, extended release	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	Boxed warning
Treats	Pain	Pain

opana er ultiva

Rating

New

70/100

Pharmacy pays

~$36.74 /30

—

Type

Active ingredient

OXYMORPHONE HYDROCHLORIDE

REMIFENTANIL HYDROCHLORIDE

Manufacturer

Endo Operations

Mylan Institutional

Dosage forms

Tablet, extended release

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Boxed warning

Treats

Pain

Frequently asked questions

What is the difference between Opana ER and Ultiva?

Opana ER contains Oxymorphone Hydrochloride, while Ultiva contains Remifentanil Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.