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ONYDA XR vs PERMAX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. ONYDA XR and PERMAX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$1.05 /30

Type

RX
RX

Active ingredient

CLONIDINE HYDROCHLORIDE
PERGOLIDE MESYLATE

Dosage forms

Suspension, extended release
Tablet

Drug class

Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Half-life

about 12 to 16 hours

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea
Tourette Syndrome, Parkinson Disease

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Frequently asked questions

Which is better-rated, Onyda XR or Permax?

By our independent rating, Onyda XR scores higher — 3.6 vs 3.5 out of 5 for Permax. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Onyda XR and Permax?

Onyda XR contains Clonidine Hydrochloride, while Permax contains Pergolide Mesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.