ONMEL vs TOLSURA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	ONMEL	TOLSURA
Rating	New	70/100
Pharmacy pays	$0.84 /mL	$0.84 /mL
Type	RX	RX
Active ingredient	ITRACONAZOLE	ITRACONAZOLE
Manufacturer	Sebela Ireland Ltd	Mayne Pharma
Dosage forms	Tablet	Capsule
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	Boxed warning
Half-life	Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.	Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.
Treats	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

onmel tolsura

Rating

New

70/100

Pharmacy pays

$0.84 /mL

Type

Active ingredient

ITRACONAZOLE

Manufacturer

Sebela Ireland Ltd

Mayne Pharma

Dosage forms

Tablet

Capsule

Drug class

Azole Antifungal

Boxed warning

None

Boxed warning

Half-life

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Frequently asked questions

Which is cheaper, Onmel or Tolsura?

Pharmacies pay about the same to acquire either one — roughly $0.84 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Onmel and Tolsura?

Both Onmel and Tolsura share the active ingredient Itraconazole.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.