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ONMEL vs SPECTAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. ONMEL and SPECTAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$0.84 /mL
$0.36 /g

Type

RX
RX

Active ingredient

ITRACONAZOLE
ECONAZOLE NITRATE

Dosage forms

Tablet
Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Half-life

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis
Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor

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Frequently asked questions

What is the difference between Onmel and Spectazole?

Onmel contains Itraconazole, while Spectazole contains Econazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.