OMEPRAZOLE vs PREVACID 24 HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	OMEPRAZOLE	PREVACID 24 HR
Rating	New	64/100
Pharmacy pays	~$1.52 /30	~$5.10 /30
Type	RX	OTC
Active ingredient	OMEPRAZOLE	LANSOPRAZOLE
Manufacturer	Hetero Labs Ltd III	Perrigo
Dosage forms	Capsule, Capsule, delayed release, Oral pellets, Tablet, delayed release, Tablet, orally disintegrating, delayed release	Capsule, delayed release
Drug class	Proton Pump Inhibitor	Proton Pump Inhibitor
Boxed warning	None	None
Half-life	about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults	about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours
Treats	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

omeprazole prevacid 24 hr

Rating

New

64/100

Pharmacy pays

~$1.52 /30

~$5.10 /30

Type

OTC

Active ingredient

OMEPRAZOLE

LANSOPRAZOLE

Manufacturer

Hetero Labs Ltd III

Perrigo

Dosage forms

Capsule, Capsule, delayed release, Oral pellets, Tablet, delayed release, Tablet, orally disintegrating, delayed release

Capsule, delayed release

Drug class

Proton Pump Inhibitor

Boxed warning

None

Half-life

about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults

about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

Which is cheaper, Omeprazole or Prevacid 24 Hr?

Omeprazole costs pharmacies less to acquire — about $1.52 vs $5.10 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Omeprazole and Prevacid 24 Hr?

Omeprazole contains Omeprazole, while Prevacid 24 Hr contains Lansoprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.