OLANZAPINE vs RISPERDAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. OLANZAPINE and RISPERDAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OLANZAPINE	RISPERDAL
Rating	New	70/100
Pharmacy pays	~$4.13 /30	~$2.07 /30
Type	RX	RX
Active ingredient	OLANZAPINE	RISPERIDONE
Manufacturer	Sun Pharm Inds Inc	Janssen Pharms
Dosage forms	Injectable, Tablet, Tablet, orally disintegrating	Solution, Tablet
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	None	Boxed warning
Half-life	about 21 to 54 hours (mean around 30 hours)	about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)
Treats	Bipolar Disorder, Psychotic Disorders, Schizophrenia	Autistic Disorder, Bipolar Disorder, Dementia

olanzapine risperdal

Rating

New

70/100

Pharmacy pays

~$4.13 /30

~$2.07 /30

Type

Active ingredient

OLANZAPINE

RISPERIDONE

Manufacturer

Sun Pharm Inds Inc

Janssen Pharms

Dosage forms

Injectable, Tablet, Tablet, orally disintegrating

Solution, Tablet

Drug class

Atypical Antipsychotic

Boxed warning

None

Boxed warning

Half-life

about 21 to 54 hours (mean around 30 hours)

about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Bipolar Disorder, Psychotic Disorders, Schizophrenia

Autistic Disorder, Bipolar Disorder, Dementia

Frequently asked questions

Which is cheaper, Olanzapine or Risperdal?

Risperdal costs pharmacies less to acquire — about $2.07 vs $4.13 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Olanzapine and Risperdal?

Olanzapine contains Olanzapine, while Risperdal contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.