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NUBAIN vs STADOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. NUBAIN and STADOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

$4.32 /mL
$14.72 /mL

Type

RX
RX

Active ingredient

NALBUPHINE HYDROCHLORIDE
BUTORPHANOL TARTRATE

Dosage forms

Solution
Injectable, Spray/Inhaler, metered

Drug class

Opioid Agonist/Antagonist
Opioid Agonist/Antagonist

Boxed warning

None
None

Treats

Postoperative Pain
Pain

Frequently asked questions

Which is cheaper, Nubain or Stadol?

Nubain costs pharmacies less to acquire — about $4.32 vs $14.72 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Nubain and Stadol?

Nubain contains Nalbuphine Hydrochloride, while Stadol contains Butorphanol Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.