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nubain

Nubain (Nalbuphine Hydrochloride) is an opioid agonist/antagonist used to treat Postoperative Pain.

Nalbuphine Hydrochloride · by Ph Health

Available as a generic: Nalbuphine Hydrochloride

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Nalbuphine Hydrochloride
Form
Solution
Strength
Nalbuphine Hydrochloride 100MG/10ML (10MG/ML) **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Nalbuphine Hydrochloride 10MG/ML (10MG/ML) **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Nalbuphine Hydrochloride 200MG/10ML (20MG/ML) **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Nalbuphine Hydrochloride 20MG/2ML (10MG/ML) **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Nalbuphine Hydrochloride 20MG/ML (20MG/ML) **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Ph Health
What the pharmacy pays
~$4.32 per ml — not your price
FDA application
NDA018024
Availability
Discontinued (per FDA)

Drug class

May treat (source: NIH RxClass)

Dosage forms

Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Nubain treat?
Nubain (Nalbuphine Hydrochloride) may be used to treat postoperative pain, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Nubain cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.32 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Nubain?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Nubain. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Nubain?
Nubain is marketed by Ph Health. You can see Ph Health's full profile, rating, and other products on pharmaranks.
Is Nubain a brand-name or generic drug?
Nubain is a brand-name product with the active ingredient Nalbuphine Hydrochloride. Lower-cost generic equivalents containing Nalbuphine Hydrochloride are available — ask your pharmacist.
Is Nubain available over the counter?
No. Nubain is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Nubain come in?
Nubain is currently marketed as solution, per the FDA's National Drug Code Directory.
What class of drug is Nubain?
Nubain is classified as opioid agonist/antagonist, per the FDA's Established Pharmacologic Class.
Is Nubain FDA-registered?
Nubain is on record with the U.S. FDA under application number NDA018024. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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