NORTRIPTYLINE HYDROCHLORIDE vs TOFRANIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. NORTRIPTYLINE HYDROCHLORIDE and TOFRANIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NORTRIPTYLINE HYDROCHLORIDE	TOFRANIL
Rating	68/100	70/100
Pharmacy pays	$0.17 /mL	~$2.54 /30
Type	RX	RX
Active ingredient	NORTRIPTYLINE HYDROCHLORIDE	IMIPRAMINE HYDROCHLORIDE
Manufacturer	Aurobindo Pharma Ltd	Novartis
Dosage forms	Capsule, Solution	Tablet, Injectable
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Treats	Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

nortriptyline hydrochloride tofranil

Rating

68/100

70/100

Pharmacy pays

$0.17 /mL

~$2.54 /30

Type

Active ingredient

NORTRIPTYLINE HYDROCHLORIDE

IMIPRAMINE HYDROCHLORIDE

Manufacturer

Aurobindo Pharma Ltd

Novartis

Dosage forms

Capsule, Solution

Tablet, Injectable

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

Get nortriptyline hydrochloride

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Frequently asked questions

Which is better-rated, Nortriptyline Hydrochloride or Tofranil?

By our independent rating, Tofranil scores higher — 3.5 vs 3.4 out of 5 for Nortriptyline Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Nortriptyline Hydrochloride and Tofranil?

Nortriptyline Hydrochloride contains Nortriptyline Hydrochloride, while Tofranil contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.