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NAMENDA vs NAMENDA XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

72/100
72/100

Pharmacy pays

~$2.46 /30
~$2.46 /30

Type

RX
RX

Active ingredient

MEMANTINE HYDROCHLORIDE
MEMANTINE HYDROCHLORIDE

Manufacturer

Dosage forms

Kit, Tablet
Capsule, extended release

Drug class

N-Methyl-D-Aspartate Receptor Antagonist
N-Methyl-D-Aspartate Receptor Antagonist

Boxed warning

None
None

Half-life

about 60 to 80 hours
about 60 to 80 hours

Treats

Alzheimer Disease
Alzheimer Disease

Frequently asked questions

Which is better-rated, Namenda or Namenda XR?

Namenda and Namenda XR are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Namenda or Namenda XR?

Pharmacies pay about the same to acquire either one — roughly $2.46 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Namenda and Namenda XR?

Both Namenda and Namenda XR share the active ingredient Memantine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.