namenda xr

How long does Memantine Hydrochloride stay in your body?

The elimination half-life of memantine hydrochloride is about 60 to 80 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal elimination half-life the label reports for memantine itself; the label gives it as a range and does not narrow it further. Memantine is not a prodrug, and it has no long-lasting active metabolite to worry about: roughly 48% of a dose is excreted unchanged in urine, and the label describes the three metabolites it does form (the N-glucuronide conjugate, 6-hydroxy memantine, and 1-nitroso-deaminated memantine) as possessing only minimal NMDA-receptor antagonistic activity. Populations the label names: in older adults, the label states that the pharmacokinetics in young and elderly subjects are similar. In kidney impairment, the terminal elimination half-life is longer — increased by about 18% in mild, 41% in moderate, and 95% (roughly double) in severe renal impairment. In moderate liver impairment (Child-Pugh B), the terminal half-life increased by about 16%, with overall exposure unchanged; severe hepatic impairment has not been evaluated.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — MEMANTINE HYDROCHLORIDE (memantine tablet, film coated), §12.3 Pharmacokinetics.

Frequently asked questions

What does Namenda XR treat?

Namenda XR (Memantine Hydrochloride) may be used to treat alzheimer disease, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How is Namenda XR rated?

pharmaranks gives Namenda XR a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Namenda XR cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.46 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Namenda XR?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Namenda XR. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Namenda XR?

Namenda XR is marketed by Abbvie. You can see Abbvie's full profile, rating, and other products on pharmaranks.

Is Namenda XR a brand-name or generic drug?

Namenda XR is a brand-name product with the active ingredient Memantine Hydrochloride. Lower-cost generic equivalents containing Memantine Hydrochloride are available — ask your pharmacist.

Is Namenda XR available over the counter?

No. Namenda XR is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Namenda XR come in?

Namenda XR is currently marketed as capsule, extended release, per the FDA's National Drug Code Directory.

What class of drug is Namenda XR?

Namenda XR is classified as n-methyl-d-aspartate receptor antagonist, per the FDA's Established Pharmacologic Class.

Is Namenda XR FDA-registered?

Namenda XR is on record with the U.S. FDA under application number NDA022525. You can verify this on its official FDA label.

Has Namenda XR been recalled by the FDA?

Namenda XR has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Namenda XR safe?

There's no single safe-or-not verdict. pharmaranks gives Namenda XR a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.