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NALBUPHINE HYDROCHLORIDE vs NUBAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

72/100
New

Pharmacy pays

$4.32 /mL
$4.32 /mL

Type

RX
RX

Active ingredient

NALBUPHINE HYDROCHLORIDE
NALBUPHINE HYDROCHLORIDE

Manufacturer

Dosage forms

Injectable, Solution
Solution

Drug class

Opioid Agonist/Antagonist
Opioid Agonist/Antagonist

Boxed warning

None
None

Treats

Postoperative Pain
Postoperative Pain

Frequently asked questions

Which is cheaper, Nalbuphine Hydrochloride or Nubain?

Pharmacies pay about the same to acquire either one — roughly $4.32 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Nalbuphine Hydrochloride and Nubain?

Both Nalbuphine Hydrochloride and Nubain share the active ingredient Nalbuphine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.