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MONISTAT 3 COMBINATION PACK (PREFILLED) vs ONMEL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Rating

70/100
New

Pharmacy pays

$0.84 /mL

Type

OTC
RX

Active ingredient

MICONAZOLE NITRATE
ITRACONAZOLE

Dosage forms

Kit
Tablet

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Half-life

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis
Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Monistat 3 Combination Pack (Prefilled) and Onmel?

Monistat 3 Combination Pack (Prefilled) contains Miconazole Nitrate, while Onmel contains Itraconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.