LEVOMILNACIPRAN HYDROCHLORIDE vs VENLAFAXINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. LEVOMILNACIPRAN HYDROCHLORIDE and VENLAFAXINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LEVOMILNACIPRAN HYDROCHLORIDE	VENLAFAXINE HYDROCHLORIDE
Rating	72/100	New
Pharmacy pays	—	~$3.59 /30
Type	RX	RX
Active ingredient	LEVOMILNACIPRAN HYDROCHLORIDE	VENLAFAXINE HYDROCHLORIDE
Manufacturer	Prinston Inc	Abon Pharms LLC
Dosage forms	Capsule, extended release	Capsule, extended release, Tablet, extended release
Drug class	Serotonin and Norepinephrine Reuptake Inhibitor	Serotonin and Norepinephrine Reuptake Inhibitor
Boxed warning	None	Boxed warning
Half-life	about 12 hours	about 5 hours (mean roughly 5 ± 2 hours) for the parent drug venlafaxine in adults with normal organ function
Treats	Major Depressive Disorder	Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Depressive Disorder

levomilnacipran hydrochloride venlafaxine hydrochloride

Rating

72/100

New

Pharmacy pays

—

~$3.59 /30

Type

Active ingredient

LEVOMILNACIPRAN HYDROCHLORIDE

VENLAFAXINE HYDROCHLORIDE

Manufacturer

Prinston Inc

Abon Pharms LLC

Dosage forms

Capsule, extended release

Capsule, extended release, Tablet, extended release

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor

Boxed warning

None

Boxed warning

Half-life

about 12 hours

about 5 hours (mean roughly 5 ± 2 hours) for the parent drug venlafaxine in adults with normal organ function

Treats

Major Depressive Disorder

Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Depressive Disorder

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Frequently asked questions

What is the difference between Levomilnacipran Hydrochloride and Venlafaxine Hydrochloride?

Levomilnacipran Hydrochloride contains Levomilnacipran Hydrochloride, while Venlafaxine Hydrochloride contains Venlafaxine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.