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LEVOLET vs METHIMAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. LEVOLET and METHIMAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$1.79 /30
~$2.28 /30

Type

RX
RX

Active ingredient

LEVOTHYROXINE SODIUM
METHIMAZOLE

Dosage forms

Tablet
Tablet

Drug class

L-Thyroxine
Thyroid Hormone Synthesis Inhibitor

Boxed warning

None
None

Half-life

about 6 to 7 days in adults with normal thyroid function
—

Treats

Goiter, Myxedema, Thyroid Neoplasms
Goiter, Thyroid Crisis

Frequently asked questions

Which is cheaper, Levolet or Methimazole?

Levolet costs pharmacies less to acquire — about $1.79 vs $2.28 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Levolet and Methimazole?

Levolet contains Levothyroxine Sodium, while Methimazole contains Methimazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.