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levolet

Levolet (Levothyroxine Sodium) is a l-thyroxine used to treat Goiter, Myxedema, Thyroid Neoplasms, Autoimmune Thyroiditis.

Levothyroxine Sodium · by Genus Lifesciences

Available as a generic: Levothyroxine Sodium

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated August 20, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Levothyroxine Sodium
Drug class
L-Thyroxine
Form
Tablet
Strength
Levothyroxine Sodium 0.025MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.05MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.075MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.088MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.112MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.125MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.137MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.15MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.175MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.1MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.2MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium · Levothyroxine Sodium 0.3MG **See Current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Genus Lifesciences
Half-life
about 6 to 7 days in adults with normal thyroid function (how long it stays in your system)
What the pharmacy pays
~$1.83 for 30 — not your price
FDA application
NDA021137

Foods & drinks to be careful with

Well-established interactions for this medicine’s drug class, summarized from public health authorities. General information, not medical advice — always confirm with your pharmacist or the label.

  • High-fibre foods and fibre supplements

    Watch out for: beans, lentils, bran, whole grains, and psyllium or other fibre supplements — plus soybean flour and walnuts.

    Fibre binds levothyroxine in the gut so less of it is absorbed. The Synthroid label names soybean flour, cottonseed meal, walnuts and dietary fibre as things that may bind and decrease absorption.

    What to do: Keep taking the fibre — the fix is separation, not avoidance. Levothyroxine is taken on an empty stomach, and a consistent gap from high-fibre food and supplements matters more than the exact size of the gap. If you start or stop a fibre supplement, tell your prescriber: your dose may need re-checking.

    Source: SYNTHROID (levothyroxine sodium) — FDA label, Drug Interactions (DailyMed)

How long does Levothyroxine Sodium stay in your body?

The elimination half-life of levothyroxine sodium is about 6 to 7 days in adults with normal thyroid function — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Half-life varies markedly with thyroid status: roughly 9 to 10 days in hypothyroidism (the condition being treated) and only 3 to 4 days in hyperthyroidism. This is the parent hormone (T4); its active product T3 has a shorter, not longer, half-life, so no longer-lived active metabolite applies.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: SYNTHROID (levothyroxine sodium) tablets — DailyMed label.

Drug class

How this class works, per Levothyroxine - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Levolet ranks — best-rated l-thyroxine for:

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Levolet treat?
Levolet (Levothyroxine Sodium) may be used to treat goiter, myxedema, thyroid neoplasms, autoimmune thyroiditis, thyrotoxicosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Levolet work?
Levolet is a l-thyroxine. L-thyroxine is a synthetic copy of the thyroid hormone T4. It replaces the hormone an underactive thyroid can't make and is converted in the body to active T3, which enters cells to restore normal metabolism and energy levels.
How much does Levolet cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.83 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Levolet?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Levolet. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Levolet?
Levolet is marketed by Genus Lifesciences. You can see Genus Lifesciences's full profile, rating, and other products on pharmaranks.
Is Levolet a brand-name or generic drug?
Levolet is a brand-name product with the active ingredient Levothyroxine Sodium. Lower-cost generic equivalents containing Levothyroxine Sodium are available — ask your pharmacist.
Is Levolet available over the counter?
No. Levolet is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Levolet come in?
Levolet is currently marketed as tablet, per the FDA's National Drug Code Directory.
What class of drug is Levolet?
Levolet is classified as l-thyroxine, per the FDA's Established Pharmacologic Class.
Is Levolet FDA-registered?
Levolet is on record with the U.S. FDA under application number NDA021137. You can verify this on its official FDA label.
Has Levolet been recalled by the FDA?
Levolet has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Levolet safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Levolet. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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