KADIAN vs OPANA ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. KADIAN and OPANA ER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	KADIAN	OPANA ER
Rating	72/100	New
Pharmacy pays	$2.61 /mL	~$36.74 /30
Type	RX	RX
Active ingredient	MORPHINE SULFATE	OXYMORPHONE HYDROCHLORIDE
Manufacturer	Allergan	Endo Operations
Dosage forms	Capsule, extended release	Tablet, extended release
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 2 hours	—
Treats	Dyspnea, Intractable Pain	Pain

kadian opana er

Rating

72/100

New

Pharmacy pays

$2.61 /mL

~$36.74 /30

Type

Active ingredient

MORPHINE SULFATE

OXYMORPHONE HYDROCHLORIDE

Manufacturer

Allergan

Endo Operations

Dosage forms

Capsule, extended release

Tablet, extended release

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 2 hours

—

Treats

Dyspnea, Intractable Pain

Pain

Frequently asked questions

What is the difference between Kadian and Opana ER?

Kadian contains Morphine Sulfate, while Opana ER contains Oxymorphone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.