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JUNIOR STRENGTH MOTRIN vs LODINE XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. JUNIOR STRENGTH MOTRIN and LODINE XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.04 /mL
~$22.58 /30

Type

RX
RX

Active ingredient

IBUPROFEN
ETODOLAC

Dosage forms

Tablet, chewable, Tablet
Tablet, extended release

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 1.8 to 2.0 hours
about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis
Rheumatoid Arthritis, Osteoarthritis, Pain

Frequently asked questions

What is the difference between Junior Strength Motrin and Lodine XL?

Junior Strength Motrin contains Ibuprofen, while Lodine XL contains Etodolac — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.