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JAKAFI vs JAKAFI XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

Type

RX
RX

Active ingredient

RUXOLITINIB PHOSPHATE
RUXOLITINIB PHOSPHATE

Dosage forms

Tablet
Tablet, extended release

Drug class

Janus Kinase Inhibitor
Janus Kinase Inhibitor

Boxed warning

None
None

Treats

Polycythemia Vera, Primary Myelofibrosis
Polycythemia Vera, Primary Myelofibrosis

Frequently asked questions

What is the difference between Jakafi and Jakafi XR?

Both Jakafi and Jakafi XR share the active ingredient Ruxolitinib Phosphate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.