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INDOMETHACIN vs SULINDAC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. INDOMETHACIN and SULINDAC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
64/100

Pharmacy pays

~$4.06 /30
~$6.27 /30

Type

RX
RX

Active ingredient

INDOMETHACIN
SULINDAC

Dosage forms

Capsule, Capsule, extended release, Suppository
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 4.5 hours

Treats

Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus
Rheumatoid Arthritis, Bursitis, Inflammation

Frequently asked questions

Which is better-rated, Indomethacin or Sulindac?

By our independent rating, Indomethacin scores higher — 3.6 vs 3.2 out of 5 for Sulindac. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Indomethacin or Sulindac?

Indomethacin costs pharmacies less to acquire — about $4.06 vs $6.27 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Indomethacin and Sulindac?

Indomethacin contains Indomethacin, while Sulindac contains Sulindac — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.