INDOMETHACIN vs PROLENSA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. INDOMETHACIN and PROLENSA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	INDOMETHACIN	PROLENSA
Rating	72/100	New
Pharmacy pays	~$4.06 /30	$14.72 /mL
Type	RX	RX
Active ingredient	INDOMETHACIN	BROMFENAC SODIUM
Manufacturer	Rising	Bausch and Lomb
Dosage forms	Capsule, Capsule, extended release, Suppository	Drops
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 4.5 hours	—
Treats	Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus	Inflammation, Postoperative Pain, Eye Pain

indomethacin prolensa

Rating

72/100

New

Pharmacy pays

~$4.06 /30

$14.72 /mL

Type

Active ingredient

INDOMETHACIN

BROMFENAC SODIUM

Manufacturer

Rising

Bausch and Lomb

Dosage forms

Capsule, Capsule, extended release, Suppository

Drops

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 4.5 hours

—

Treats

Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

Inflammation, Postoperative Pain, Eye Pain

Frequently asked questions

What is the difference between Indomethacin and Prolensa?

Indomethacin contains Indomethacin, while Prolensa contains Bromfenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.