HYGROTON vs THALITONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	HYGROTON	THALITONE
Rating	70/100	New
Pharmacy pays	~$2.67 /30	~$2.67 /30
Type	RX	RX
Active ingredient	CHLORTHALIDONE	CHLORTHALIDONE
Manufacturer	Sanofi Aventis US	Casper Pharma LLC
Dosage forms	Tablet	Tablet
Drug class	Thiazide-Like Diuretic	Thiazide-Like Diuretic
Boxed warning	None	None
Half-life	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)
Treats	Edema, Glomerulonephritis, Heart Failure	Edema, Glomerulonephritis, Heart Failure

hygroton thalitone

Rating

70/100

New

Pharmacy pays

~$2.67 /30

Type

Active ingredient

CHLORTHALIDONE

Manufacturer

Sanofi Aventis US

Casper Pharma LLC

Dosage forms

Tablet

Drug class

Thiazide-Like Diuretic

Boxed warning

None

Half-life

about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)

Treats

Edema, Glomerulonephritis, Heart Failure

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Frequently asked questions

Which is cheaper, Hygroton or Thalitone?

Pharmacies pay about the same to acquire either one — roughly $2.67 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Hygroton and Thalitone?

Both Hygroton and Thalitone share the active ingredient Chlorthalidone.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.