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HYDROXYZINE PAMOATE vs VISTARIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. HYDROXYZINE PAMOATE and VISTARIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

hydroxyzine pamoatevistaril

Rating

70/100
64/100

Pharmacy pays

—
$0.04 /mL

Type

RX
RX

Active ingredient

HYDROXYZINE PAMOATE
HYDROXYZINE HYDROCHLORIDE

Manufacturer

Watson Labs
Pfizer

Dosage forms

Capsule
Capsule, Injectable

Drug class

Antihistamine
Antihistamine

Boxed warning

None
None

Half-life

about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)
about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)

Treats

Anxiety Disorders, Nausea, Pruritus
Anxiety Disorders, Nausea, Pruritus

Frequently asked questions

Which is better-rated, Hydroxyzine Pamoate or Vistaril?

By our independent rating, Hydroxyzine Pamoate scores higher — 3.5 vs 3.2 out of 5 for Vistaril. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Hydroxyzine Pamoate and Vistaril?

Hydroxyzine Pamoate contains Hydroxyzine Pamoate, while Vistaril contains Hydroxyzine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.