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GEODON vs SAPHRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. GEODON and SAPHRIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$9.47 /30
~$73.98 /30

Type

RX
RX

Active ingredient

ZIPRASIDONE HYDROCHLORIDE
ASENAPINE MALEATE

Manufacturer

Dosage forms

Capsule, Injectable
Tablet

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Boxed warning

Half-life

—
about 24 hours (terminal/elimination half-life)

Treats

Tourette Syndrome, Schizophrenia
Bipolar Disorder, Schizophrenia

Frequently asked questions

Which is better-rated, Geodon or Saphris?

By our independent rating, Geodon scores higher — 3.6 vs 3.5 out of 5 for Saphris. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Geodon or Saphris?

Geodon costs pharmacies less to acquire — about $9.47 vs $73.98 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Geodon and Saphris?

Geodon contains Ziprasidone Hydrochloride, while Saphris contains Asenapine Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.