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GABITRIL vs ZONEGRAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. GABITRIL and ZONEGRAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$63.70 /30
~$3.16 /30

Type

RX
RX

Active ingredient

TIAGABINE HYDROCHLORIDE
ZONISAMIDE

Dosage forms

Tablet
Capsule

Drug class

Anti-Epileptic Agent
Anti-Epileptic Agent

Boxed warning

None
None

Treats

Bipolar Disorder, Partial Epilepsies
Partial Epilepsies

Frequently asked questions

Which is cheaper, Gabitril or Zonegran?

Zonegran costs pharmacies less to acquire — about $3.16 vs $63.70 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Gabitril and Zonegran?

Gabitril contains Tiagabine Hydrochloride, while Zonegran contains Zonisamide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.