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FLONASE ALLERGY RELIEF vs LOCOID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

72/100
New

Pharmacy pays

Type

OTC
RX

Active ingredient

FLUTICASONE PROPIONATE
HYDROCORTISONE BUTYRATE

Dosage forms

Spray/Inhaler, metered
Topical, Solution

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Half-life

about 1.5 hours

Treats

Perennial Allergic Rhinitis
Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Flonase Allergy Relief and Locoid?

Flonase Allergy Relief contains Fluticasone Propionate, while Locoid contains Hydrocortisone Butyrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.