FAMOTIDINE vs ZANTAC 300

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. FAMOTIDINE and ZANTAC 300 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FAMOTIDINE	ZANTAC 300
Rating	70/100	70/100
Pharmacy pays	~$1.54 /30	—
Type	RX	RX
Active ingredient	FAMOTIDINE	RANITIDINE HYDROCHLORIDE
Manufacturer	Micro Labs	Glaxosmithkline
Dosage forms	Injectable, Solution, Powder, Tablet	Capsule, Tablet
Drug class	Histamine-2 Receptor Antagonist	—
Boxed warning	None	None
Half-life	2.5 to 3.5 hours	about 2.5 to 3 hours
Treats	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis	Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

famotidine zantac 300

Rating

70/100

Pharmacy pays

~$1.54 /30

—

Type

Active ingredient

FAMOTIDINE

RANITIDINE HYDROCHLORIDE

Manufacturer

Micro Labs

Glaxosmithkline

Dosage forms

Injectable, Solution, Powder, Tablet

Capsule, Tablet

Drug class

Histamine-2 Receptor Antagonist

—

Boxed warning

None

Half-life

2.5 to 3.5 hours

about 2.5 to 3 hours

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

Which is better-rated, Famotidine or Zantac 300?

Famotidine and Zantac 300 are tied at 3.5 out of 5 by our independent rating.

What is the difference between Famotidine and Zantac 300?

Famotidine contains Famotidine, while Zantac 300 contains Ranitidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.