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DOXYCYCLINE HYCLATE vs PERIOSTAT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

70/100
New

Pharmacy pays

$0.12 /mL
$0.12 /mL

Type

RX
RX

Active ingredient

DOXYCYCLINE HYCLATE
DOXYCYCLINE HYCLATE

Dosage forms

Capsule, Powder, Tablet, Tablet, delayed release
Capsule, Tablet

Drug class

Tetracycline-Class Drug
Tetracycline-Class Drug

Boxed warning

None
None

Half-life

about 16 to 22 hours in healthy adults
about 16 to 22 hours in healthy adults

Treats

Anthrax, Campylobacter Infections, Cholera
Anthrax, Campylobacter Infections, Cholera

Frequently asked questions

Which is cheaper, Doxycycline Hyclate or Periostat?

Pharmacies pay about the same to acquire either one — roughly $0.12 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Doxycycline Hyclate and Periostat?

Both Doxycycline Hyclate and Periostat share the active ingredient Doxycycline Hyclate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.