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DIVALPROEX SODIUM vs ZONEGRAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DIVALPROEX SODIUM and ZONEGRAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

divalproex sodiumzonegran

Rating

68/100
New

Pharmacy pays

~$5.99 /30
~$3.16 /30

Type

RX
RX

Active ingredient

DIVALPROEX SODIUM
ZONISAMIDE

Manufacturer

Aurobindo Pharma Ltd
Advanz Pharma

Dosage forms

Capsule, Oral pellets, Capsule, delayed release, Tablet, delayed release, Tablet, extended release
Capsule

Drug class

Anti-Epileptic Agent
Anti-Epileptic Agent

Boxed warning

Boxed warning
None

Half-life

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
—

Treats

Bipolar Disorder, Epilepsy, Absence Epilepsy
Partial Epilepsies

Frequently asked questions

Which is cheaper, Divalproex Sodium or Zonegran?

Zonegran costs pharmacies less to acquire — about $3.16 vs $5.99 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Divalproex Sodium and Zonegran?

Divalproex Sodium contains Divalproex Sodium, while Zonegran contains Zonisamide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.