DISIPAL vs FLEXERIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. DISIPAL and FLEXERIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DISIPAL	FLEXERIL
Rating	New	New
Pharmacy pays	$0.48 /mL	~$0.63 /30
Type	RX	RX
Active ingredient	ORPHENADRINE HYDROCHLORIDE	CYCLOBENZAPRINE HYDROCHLORIDE
Manufacturer	3m	Janssen Res and Dev
Dosage forms	Tablet	Tablet
Drug class	Muscle Relaxant	Muscle Relaxant
Boxed warning	None	None
Half-life	—	about 18 hours (range roughly 8 to 37 hours) for the standard immediate-release tablet in typical adults
Treats	Muscle Cramp, Muscle Rigidity, Myositis	Muscle Cramp, Muscle Rigidity, Muscle Spasticity

disipal flexeril

Rating

New

Pharmacy pays

$0.48 /mL

~$0.63 /30

Type

Active ingredient

ORPHENADRINE HYDROCHLORIDE

CYCLOBENZAPRINE HYDROCHLORIDE

Manufacturer

Janssen Res and Dev

Dosage forms

Tablet

Drug class

Muscle Relaxant

Boxed warning

None

Half-life

—

about 18 hours (range roughly 8 to 37 hours) for the standard immediate-release tablet in typical adults

Treats

Muscle Cramp, Muscle Rigidity, Myositis

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

What is the difference between Disipal and Flexeril?

Disipal contains Orphenadrine Hydrochloride, while Flexeril contains Cyclobenzaprine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.