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DILAUDID-HP vs PALLADONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

68/100
New

Pharmacy pays

$0.57 /mL
$0.57 /mL

Type

RX
RX

Active ingredient

HYDROMORPHONE HYDROCHLORIDE
HYDROMORPHONE HYDROCHLORIDE

Dosage forms

Injectable
Capsule, extended release

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid
about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid

Treats

Cough, Postoperative Pain
Cough, Postoperative Pain

Frequently asked questions

Which is cheaper, Dilaudid-Hp or Palladone?

Pharmacies pay about the same to acquire either one — roughly $0.57 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Dilaudid-Hp and Palladone?

Both Dilaudid-Hp and Palladone share the active ingredient Hydromorphone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.