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DICLOFENAC POTASSIUM vs INDOMETHACIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DICLOFENAC POTASSIUM and INDOMETHACIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

$0.36 /mL
~$4.06 /30

Type

RX
RX

Active ingredient

DICLOFENAC POTASSIUM
INDOMETHACIN

Manufacturer

Dosage forms

Capsule, Powder, Tablet
Capsule, Capsule, extended release, Suppository

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
about 4.5 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea
Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

Frequently asked questions

What is the difference between Diclofenac Potassium and Indomethacin?

Diclofenac Potassium contains Diclofenac Potassium, while Indomethacin contains Indomethacin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.