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DEXILANT SOLUTAB vs PRILOSEC OTC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

New
70/100

Pharmacy pays

~$126.41 /30

Type

RX
OTC

Active ingredient

DEXLANSOPRAZOLE
OMEPRAZOLE MAGNESIUM

Dosage forms

Tablet, orally disintegrating, delayed release
Tablet, delayed release

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Half-life

about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults

Treats

Peptic Esophagitis, Gastroesophageal Reflux, Heartburn
Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

Get prilosec otchigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Dexilant Solutab and Prilosec OTC?

Dexilant Solutab contains Dexlansoprazole, while Prilosec OTC contains Omeprazole Magnesium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.