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DESVENLAFAXINE SUCCINATE vs MILNACIPRAN HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. DESVENLAFAXINE SUCCINATE and MILNACIPRAN HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

desvenlafaxine succinatemilnacipran hydrochloride

Rating

70/100
New

Pharmacy pays

~$115.24 /30
~$97.10 /30

Type

RX
RX

Active ingredient

DESVENLAFAXINE SUCCINATE
MILNACIPRAN HYDROCHLORIDE

Manufacturer

Actavis Labs Fl Inc
Hetero Labs Ltd V

Dosage forms

Tablet, extended release
Tablet, Kit

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor
Serotonin and Norepinephrine Reuptake Inhibitor

Boxed warning

Boxed warning
Boxed warning

Treats

Major Depressive Disorder
Major Depressive Disorder

Frequently asked questions

Which is cheaper, Desvenlafaxine Succinate or Milnacipran Hydrochloride?

Milnacipran Hydrochloride costs pharmacies less to acquire — about $97.10 vs $115.24 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Desvenlafaxine Succinate and Milnacipran Hydrochloride?

Desvenlafaxine Succinate contains Desvenlafaxine Succinate, while Milnacipran Hydrochloride contains Milnacipran Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.