DEPAKOTE vs ZONEGRAN
Independent side-by-side comparison.
Possible drug interaction. DEPAKOTE and ZONEGRAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.
Rating
Pharmacy pays
Type
Active ingredient
Manufacturer
Dosage forms
Drug class
Boxed warning
Half-life
Treats
Frequently asked questions
Which is cheaper, Depakote or Zonegran?
Zonegran costs pharmacies less to acquire — about $3.16 vs $5.99 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.
What is the difference between Depakote and Zonegran?
Depakote contains Divalproex Sodium, while Zonegran contains Zonisamide — they have different active ingredients.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.