DEMEROL vs SUBSYS
Independent side-by-side comparison.
Possible drug interaction. DEMEROL and SUBSYS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.
Rating
Pharmacy pays
Type
Active ingredient
Manufacturer
Dosage forms
Drug class
Boxed warning
Treats
Frequently asked questions
Which is cheaper, Demerol or Subsys?
Demerol costs pharmacies less to acquire — about $0.16 vs $9.51 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.
What is the difference between Demerol and Subsys?
Demerol contains Meperidine Hydrochloride, while Subsys contains Fentanyl — they have different active ingredients.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.